The present invention relates to the discovery of novel T cell epitopes of the human prostatic acid phosphatase (PAP) protein that is promiscuous for at least 15 different HLA-DR alleles. The invention also relates to compositions that contain one of the novel epitopes or a fusion peptide of such an epitope and a heterologous polypeptide. Further disclosed herein is the use of the epitopes or their fusion peptides, and compositions containing the epitopes or their fusion peptides.
申请公布号
WO2008022030(A2)
申请公布日期
2008.02.21
申请号
WO2007US75704
申请日期
2007.08.10
申请人
DENDREON CORPORATION;WOLLAN, JAMI B.;JONES, LORI A.