发明名称 |
COMPOSITIONS ENRICHED IN NEOPLASTIC STEM CELLS AND METHODS COMPRISING SAME |
摘要 |
<p>A neoplastic stem cell population enriched for expression of the OCT4 transcription factor as well as methods for their identification, isolation and enrichment are described. The OCT4-enriched neoplastic stem cell population is further utilized for the induction and analysis of cancer in an animal. In addition, methods of preventing, abrogating, or inhibiting cancer, tumor growth, and metastasis via OCT4 inhibition are further provided.</p> |
申请公布号 |
WO2007145901(A1) |
申请公布日期 |
2007.12.21 |
申请号 |
WO2007US13167 |
申请日期 |
2007.06.05 |
申请人 |
NOVOSTEM THERAPEUTICS INC;DUNTSCH, CHRISTOPHER;KUKEKEOV, VALERY;IGANTOVA, TATYANA |
发明人 |
DUNTSCH, CHRISTOPHER;KUKEKEOV, VALERY;IGANTOVA, TATYANA |
分类号 |
C12N5/09;C12N5/095 |
主分类号 |
C12N5/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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