发明名称 |
Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment and prevention of diseases |
摘要 |
Compositions and methods of using compositions for treatment of inflammatory diseases and immune disorders are provided. Allylamino compounds are disclosed which are inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and/or vascular adhesion protein 1 (VAP-1). The compounds have therapeutic utility in suppressing inflammation and inflammatory responses, and in treatment of several disorders, including multiple sclerosis and stroke.
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申请公布号 |
US2007293548(A1) |
申请公布日期 |
2007.12.20 |
申请号 |
US20070731819 |
申请日期 |
2007.03.30 |
申请人 |
WANG ERIC Y;JONES DAVID S;O'ROURKE ANNE M;MACDONALD MARY T;GAO HONGFENG;TON-NU HUONG-THU;KESSLER CHRISTINA A;LINNIK MATTHEW D |
发明人 |
WANG ERIC Y.;JONES DAVID S.;O'ROURKE ANNE M.;MACDONALD MARY T.;GAO HONGFENG;TON-NU HUONG-THU;KESSLER CHRISTINA A.;LINNIK MATTHEW D. |
分类号 |
A61K31/44;A61K31/135;A61K31/343;A61K31/381;A61P29/00;A61P37/00;C07C211/26;C07C211/29;C07C217/54 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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