| 发明名称 |
METABOLITES FOR NK-I ANTAGONISTS FOR EMESIS. |
| 摘要 |
<p>The present invention relates to compounds of the general formula (I) wherein R is methyl; and R<sup>1</sup> is 4-methyl-4-oxy-piperazin-l-yl; or R is CH<sub>2</sub>OH and R<sup>1</sup> is 4-methyl-piperazin-l-yl or is 4-methyl-4-oxy-piperazin-l-yl; and to pharmaceutically acceptable acid addition salts thereof for the treatment of NK-I receptor related diseases.</p> |
| 申请公布号 |
MX2007011489(A) |
申请公布日期 |
2007.10.11 |
| 申请号 |
MX20070011489 |
申请日期 |
2006.03.14 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG. |
发明人 |
TORSTEN HOFFMANN.;ANDREAS KOBLET;CHRISTOPH FUNK |
| 分类号 |
C07D213/75;A61K31/44;A61P25/22;A61P25/24 |
主分类号 |
C07D213/75 |
| 代理机构 |
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