发明名称 |
Fluorinated di-aryl urea compounds |
摘要 |
Disclosed are compounds of formula(I): wherein R<SUB>1</SUB>, R<SUB>2</SUB>, W and X of formula(I) are defined herein. The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.
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申请公布号 |
US7279475(B2) |
申请公布日期 |
2007.10.09 |
申请号 |
US20040940898 |
申请日期 |
2004.09.14 |
申请人 |
BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. |
发明人 |
CIRILLO PIER FRANCESCO;HAMMACH ABDELHAKIM;KAMHI VICTOR;MOSS NEIL;RISKA PAUL S;PARGELLIS CHRISTOPHER |
分类号 |
A61K31/5377;A61K31/496;C07D239/34;C07D239/46;C07D239/52;C07D401/12;C07D403/06;C07D405/12;C07D413/06;C07D521/00 |
主分类号 |
A61K31/5377 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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