发明名称 Fluorinated di-aryl urea compounds
摘要 Disclosed are compounds of formula(I): wherein R<SUB>1</SUB>, R<SUB>2</SUB>, W and X of formula(I) are defined herein. The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.
申请公布号 US7279475(B2) 申请公布日期 2007.10.09
申请号 US20040940898 申请日期 2004.09.14
申请人 BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. 发明人 CIRILLO PIER FRANCESCO;HAMMACH ABDELHAKIM;KAMHI VICTOR;MOSS NEIL;RISKA PAUL S;PARGELLIS CHRISTOPHER
分类号 A61K31/5377;A61K31/496;C07D239/34;C07D239/46;C07D239/52;C07D401/12;C07D403/06;C07D405/12;C07D413/06;C07D521/00 主分类号 A61K31/5377
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