发明名称 5-PHENOXYALKOXYPSORALENS AND METHODS FOR SELECTIVE INHIBITION OF THE VOLTAGE GATED KV1.3 POTASSIUM CHANNEL.
摘要 <p>Compositions of matter comprising 5-phenoxyalkoxypsoralen compounds and their method of synthesis and use. The compounds are useable to treat diseases or disorders in human or animal subjects, including autoimmune diseases. The compounds inhibit potassium channels, including the Kv1.3 channel and at least some of the therapeutic effects of such compounds may be due at least in part to potassium channel inhibition. In some embodiments, the compounds are more selective for certain potassium channels (e.g., Kv1.3 channels) than other potassium channels (e.g., Kv1.5 channels).</p>
申请公布号 MX2007004073(A) 申请公布日期 2007.10.03
申请号 MX20070004073 申请日期 2005.10.04
申请人 THE REGENTS OF THE UNIVERSITY OF CALIFORNIA. 发明人 ANANTHAKRISHNAN SURIANARAYANAN;HEIKE WULFF;WOLFRAM HAENSEL;ALEXANDER SCHMITZ;KRISTINA SCHMIDT-LASSEND
分类号 A61K31/4433;C07D493/02 主分类号 A61K31/4433
代理机构 代理人
主权项
地址