发明名称 |
COMPOSITION AND METHOD FOR MEDIATING AN IMMUNE RESPONSE |
摘要 |
The present invention provides a fusion protein comprising an Fc receptor binding polypeptide and an antigenic polypeptide. The fusion protein may further comprise a linker sequence or hinge portion which joins the Fc receptor binding polypeptide and the antigenic polypeptide. The Fc receptor binding polypeptide typically comprises the CH2 constant domain of a human IgG immunoglobulin. The antigenic polypeptide can be any polypeptide which induces an immune response. Administration of the fusion protein to a subject results in a cytotoxic T lymphocyte response being induced against the antigenic polypeptide provided within the fusion protein. The invention further extends to methods for the treatment of a disease condition in a subject using the fusion proteins of the invention. |
申请公布号 |
WO2007107797(A2) |
申请公布日期 |
2007.09.27 |
申请号 |
WO2007GB50143 |
申请日期 |
2007.03.22 |
申请人 |
IMMUNOBIOLOGY LIMITED;COLACO, CAMILO |
发明人 |
COLACO, CAMILO |
分类号 |
C07K16/00 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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