| 摘要 |
Filter membranes to be used in efficiently eliminating pathogens such as viruses from solutions of drugs or physiologically active substances employed as starting materials thereof which are contaminated with pathogens such as viruses. These filter membranes, which can simultaneously achieve favorable performance of eliminating small viruses and a high physiologically active substance-permeability, can be obtained by controlling the membrane characteristics to give a ratio (BP/ gamma ) of the bubble point BP (MPa) to the surface tension gamma (N/m) of 110 or above, and/or logarithmic elimination ratios of swine parvovirus at 0 to 5 l/m<2> filtration and at 50 to 55 l/m<2> filtration of each 3 or above, and regulating the permeability for bovine immunoglobulin, wherein the monomer content amounts to at least 80%, to 70% or above. These filter membranes make it possible to provide drugs or starting materials therefor with little fear of the contamination with viruses, etc. and, therefore, are useful in the fields of pharmacy, medicine and the like.
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