FURIN INHIBITORS AND ALPHA-DEFENSINS FOR THE TREATMENT OR PREVENTION OF PAPILLOMAVIRUS INFECTION

摘要

The present invention includes a method for inhibiting papillomavirus infection in a human comprising administering to a human at risk thereof a furin inhibitor or alpha-defensin, a method of inhibiting papillomavirus infection in a human comprising transfecting a cell in vivo with an nucleic acid comprising a nucleotide sequence encoding a furin inhibitor or alpha-defensin, a method for determining whether a compound modulates furin inhibitor or alpha-defensin activity in a cell, and a method for inhibiting papillomavirus infection in a human comprising administering to the human an identified compound to augment furin inhibitor or alpha-defensin activity.