发明名称 |
PHARMACEUTICAL COMPOSITION HAVING AN INCREASED IMMUNE-STIMULATING ACTIVITY, A METHOD OF FORMING T AND USE THEREOF |
摘要 |
A pharmaceutical composition includes a physiologically active conjugate including a Thymosin alpha 1 (TA1) peptide conjugated to a material which increases half-life of the TA1 peptide in serum of a patient when the conjugate is administered to a patient. The material may be a substantially non-antigenic polymer. In a method of the invention, the substantially non-antigenic polymer is conjugated to a TA1 peptide. Compositions according to the invention are administered to patients in need of immune stimulation. |
申请公布号 |
EA008703(B1) |
申请公布日期 |
2007.06.29 |
申请号 |
EA20040000592 |
申请日期 |
2002.11.01 |
申请人 |
SCICLONE PHARMACEUTICALS, INC. |
发明人 |
RUDOLPH ALFRED, R.;TUTHILL CYNTHIA, W. |
分类号 |
A61K38/16;A61K38/17;A61K38/22;A61K47/48;A61P37/04;C07K14/00;C07K14/435;C07K14/575 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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