发明名称 INDOLIN-2-ONE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 The subject of the invention is indolin-2-one derivatives of formula: IMG> in which: - W represents a-CH2- or -SO2- group; - Cy forms, with the carbon to which it is bonded, a non-aromatic, saturated or unsaturated C3-C12 hydrocarbon ring which is optionally condensed or substituted by one or a number of (Cl-C7)alkyl groups, it being possible for the said groups to substitute the same carbon atom one or a number of times, or by a C3-C6 spirocycloalkyl; - T represents a(Cl-C4)alkylene which is optionally interrupted by a (C3-C6)cycloalkylene, the said alkylenes optionally being substituted one or a number of times on the same carbon atom by a(Cl-C3)alkyl; or alternatively T represents a direct bond; - Z represents in particular an amino group; - Rl and R2, as well as R3 and R4, are either hydrogen or substituents, such as, for example, a halogen, an alkyl, and the like. Application: Medicines having an affinity for vasopressin and/or oxytocin receptors.
申请公布号 CA2235686(C) 申请公布日期 2007.06.26
申请号 CA19962235686 申请日期 1996.10.24
申请人 SANOFI 发明人 GARCIA, GEORGES;SERRADEIL-LE GAL, CLAUDINE;FOULON, LOIC;VALETTE, GERARD
分类号 C07D209/54;C07D209/96;A61K31/40;A61K31/403;A61K31/404;A61K31/435;A61K31/4427;A61K31/445;A61K31/454;A61K31/495;A61K31/496;A61K31/535;A61K31/5377;A61K31/54;A61K31/541;A61K31/55;A61K31/675;A61K45/00;A61P1/00;A61P1/04;A61P1/16;A61P3/10;A61P5/00;A61P7/04;A61P7/10;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P11/00;A61P13/12;A61P15/00;A61P25/00;A61P25/06;A61P25/18;A61P25/22;A61P25/28;A61P25/30;A61P25/34;A61P27/02;A61P27/06;A61P27/12;A61P35/00;A61P43/00;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D405/00;C07D409/00;C07D413/12;C07D413/14 主分类号 C07D209/54
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