发明名称 |
PDE INHIBITORS AND COMBINATIONS THEREOF FOR THE TREATMENT OF UROLOGICAL DISORDERS |
摘要 |
The invention provides pharmacological compositions comprising PDE-5 and PDE-4 inhibitors, alone or in combination, for the treatment of urological disorders comprising Benign Prostate Hyperplasia (BPH), Lower Urinary Tract Symptoms (LUTS) and in particular irritative symptoms caused by BPH-induced bladder outlet obstruction (BOO). The invention also provides methods of screening for such PDE-5 and PDE-4 inhibitors for use, alone and in combination, in the preparation of medicaments for the treatment of said urological disorders. |
申请公布号 |
WO2007039075(A3) |
申请公布日期 |
2007.06.21 |
申请号 |
WO2006EP09040 |
申请日期 |
2006.09.16 |
申请人 |
BAYER HEALTHCARE AG;ULBRICH, ERNST;SANDNER, PETER;TINEL, HANNA;HUETTER, JOACHIM |
发明人 |
ULBRICH, ERNST;SANDNER, PETER;TINEL, HANNA;HUETTER, JOACHIM |
分类号 |
C12Q1/44;A61K31/00;A61P13/00 |
主分类号 |
C12Q1/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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