The present invention relates to a vaccine comprising a nucleic acid construct such as a DNA construct especially a nucleic acid construct comprising sequences encoding invariant chain operatively linked to antigenic protein or peptide encoding sequences. The vaccine stimulates an immune response, especially an immune response in an MHC-I dependent, but CD4<SUP>+</SUP> T-cell independent manner.
申请公布号
WO2007062656(A2)
申请公布日期
2007.06.07
申请号
WO2006DK00675
申请日期
2006.11.30
申请人
COPENHAGEN UNIVERSITY;HOLST, PETER JOHANNES;THOMSEN, ALLAN RANDRUP;CHRISTENSEN, JAN PRAVSGAARD
发明人
HOLST, PETER JOHANNES;THOMSEN, ALLAN RANDRUP;CHRISTENSEN, JAN PRAVSGAARD