| 摘要 |
A method for diagnosing, prognosing or monitoring the health of a subject based on mass spectrometric analysis of specific proteins in fractionated blood samples is provided. Preferable embodiment utilized MALDI-TOF technique, which is applied to monitor apolipoproteins in the samples, see Figure 1. The major biological markers include apolipoprotein CI and its modification with m/z 6631 +/- 3 and 6433 +/- 3. The ratio of intensities or integral of these peaks can be used as a reference for diagnosis specific diseases, such as diabetes. |
