TRIAZOSPIRO COMPOUND HAVING NOCICEPTIN RECEPTOR AFFINITY

摘要

PROBLEM TO BE SOLVED: To provide new compounds have affinity for ORL1 receptor, and to provide a method for treating chronic and acute pains, comprising administering an effective amount of the compound. SOLUTION: A pharmaceutical composition contains a compound of formula (I), wherein A, R1, R2, R3, R4and X1are each a selectively substituted compound. COPYRIGHT: (C)2007,JPO&INPIT