发明名称 |
INTERLEUKIN-15 ANTAGONIST PEPTIDE. |
摘要 |
<p>The invention relates to the field of molecular pharmacology and, in particular, to a peptide belonging to the Interleukin-15 (IL-15) sequence, which can inhibit the biological activity of said molecule and analogues or mimetics of the peptide. The invention demonstrates that, when bound to the alpha subunit of the receptor (IL-15R), the peptide inhibits T-cell proliferation induced by IL-15 and apoptosis caused by TNF. The invention also relates to the use of the peptide in the treatment of pathologies in which the abnormal IL-15 or IL-15R expression is related to the course of the disease.</p> |
申请公布号 |
MX2007002996(A) |
申请公布日期 |
2007.05.16 |
申请号 |
MX20070002996 |
申请日期 |
2005.09.16 |
申请人 |
CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIA |
发明人 |
SILVIO ERNESTO PEREA RODRIGUEZ;OSVALDO REYES ACOSTA;ALICIA SANTOS SAVIO;ANIA CABRALES RICO;HAYDEE GERONIMO PEREZ;CELIA AURORA ARRIETA AGUERO |
分类号 |
C07K14/54;C07K16/24;C12N15/24 |
主分类号 |
C07K14/54 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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