发明名称 |
A DEVICE FOR BINDING A TARGET ENTITY TO A BAIT ENTITY AND DETECTION METHODS USING THE SAME |
摘要 |
<p>The present invention pertains to a device for binding a target entity onto a bait entity that is immobilized on said device, comprising: a) a lipid layer having a negative net charge in an aqueous solution at a neutral pH; b) a two-dimensional matrix of anchoring complexes that are bound to said lipid layer, wherein each of said anchoring complexes comprises: (i) a fusion complex comprising an Annexin protein fused to a partner molecule; and (ii) a bait entity. It also concerns various uses of said device, including for detection and pharmaceutical purposes.</p> |
申请公布号 |
EP1756572(A1) |
申请公布日期 |
2007.02.28 |
申请号 |
EP20050746295 |
申请日期 |
2005.05.12 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);UNIVERSITE DE BORDEAUX I |
发明人 |
BRISSON, ALAIN, DENIS, RAPHAEL |
分类号 |
G01N33/543 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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