VERFAHREN UND VORRICHTUNG ZUM AUFFINDEN VON STOFFGEMISCHEN FÜR SUBSTANZBIBLIOTHEKEN

摘要

Method of discovering mixtures of substances to build up a substance library, comprises: (A) separating mixtures by chromatographic or electrophoretic means; and (B) identifying low molecule organic substances in each mixture by the physical parameters of retention time and the molecular mass registered by mass spectrometry. Method of discovering mixtures of substances to build up a substance library, comprises: (a) separating mixtures by chromatographic or electrophoretic means; and (b) identifying low molecule organic substances in each mixture by the physical parameters of retention time and the molecular mass registered by mass spectrometry. The high performance liquid chromatograph (HPLC) diagram (10) of a standard solution under standard conditions gives two peaks (12,14) for retention times of reference measurements. In a subsequent diagram (16) under laboratory conditions, the corresponding peaks (18,20) of the same substances are shifted (22,24) against the previous peaks.