| 发明名称 |
SUSTAINED RELEASE, AND COMFORTABLE OPHTHALMIC COMPOSITION AND METHOD FOR OCULAR THERAPY |
| 摘要 |
Numerous drugs cause "stinging" as a side effect when used in the eye, thus increasing patient's discomfort, partly due to the presence of preservatives present in ocular formulations. The present invention is related to a new sustained release ophthalmic formulations with reduced stinging comprising a) at least one basic active; b) a polyanionic polymer; c) an ion exchange resin; and d) a pH adjusting agent. The present invention is also directed to the use of such formulations.
|
| 申请公布号 |
CA2345466(C) |
申请公布日期 |
2007.01.23 |
| 申请号 |
CA19992345466 |
申请日期 |
1999.09.22 |
| 申请人 |
ALCON LABORATORIES, INC. |
发明人 |
WEINER, ALAN L.;SINGH, ONKAR N.;YARBOROUGH, CODY;CASTILLO, ERNESTO J.;SARKAR, RUMA |
| 分类号 |
A61K31/795;A61K47/30;A61K9/00;A61K9/08;A61K9/10;A61K31/135;A61K31/138;A61K31/215;A61K31/216;A61K31/5575;A61K31/78;A61K45/00;A61K47/04;A61K47/10;A61K47/18;A61K47/32;A61P27/02 |
主分类号 |
A61K31/795 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
