METHOD OF TREATING SYMPTOMS OF HORMONAL VARIATION, INCLUDINGHOT FLASHES

摘要

One aspect of the present invention relates to a method of treating hot flashes in a patient which is carried out by providing a compound which bind s a .alpha.2.delta. subunit of a voltage-gated calcium channel and administeri ng the compound to a patient experiencing hot flashes under conditions effectiv e to treat the hot flashes. Another aspect of the present invention relates to a method for treating a symptom of hormonal variation in a patient which is carried out by providing a compound which binds a .alpha.2.delta. subunit of a voltage-gated calcium channel and administering the compound to a patient experiencing a symptom of hormonal variation under conditions effective to treat the symptom of hormonal variation. Further aspects of the present invention relate to the administration of a compound which binds a .alpha.2.delta. subunit of a voltage-gated calcium channel as an anti-pyreti c agent (for treating fever) or as an anti-emetic agent (for treating nausea a nd emesis).