发明名称 Synthetic heparin-binding growth factor analogs
摘要 The invention provides synthetic heparin-binding growth factor analogs having at least one peptide chain that binds a heparin-binding growth factor receptor, covalently bound to a hydrophobic linker, which is in turn covalently bound to a non-signaling peptide that includes a heparin-binding domain. The synthetic heparin-binding growth factor analogs are useful as soluble biologics or as surface coatings for medical devices.
申请公布号 US7166574(B2) 申请公布日期 2007.01.23
申请号 US20020224268 申请日期 2002.08.20
申请人 BROOKHAVEN NATIONAL LABORATORY 发明人 PENA LOUIS A.;ZAMORA PAUL;LIN XINHUA;GLASS JOHN D.
分类号 A61K38/00;A61K38/19;A61L27/34;C07H21/04;C07K14/00;C07K14/50 主分类号 A61K38/00
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