发明名称 |
Synthetic heparin-binding growth factor analogs |
摘要 |
The invention provides synthetic heparin-binding growth factor analogs having at least one peptide chain that binds a heparin-binding growth factor receptor, covalently bound to a hydrophobic linker, which is in turn covalently bound to a non-signaling peptide that includes a heparin-binding domain. The synthetic heparin-binding growth factor analogs are useful as soluble biologics or as surface coatings for medical devices.
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申请公布号 |
US7166574(B2) |
申请公布日期 |
2007.01.23 |
申请号 |
US20020224268 |
申请日期 |
2002.08.20 |
申请人 |
BROOKHAVEN NATIONAL LABORATORY |
发明人 |
PENA LOUIS A.;ZAMORA PAUL;LIN XINHUA;GLASS JOHN D. |
分类号 |
A61K38/00;A61K38/19;A61L27/34;C07H21/04;C07K14/00;C07K14/50 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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