TREATMENT OF PATIENTS WITH CANCER USING A CALICHEAMICIN-ANTIBODY CONJUGATE IN COMBINATION WITH ZOSUQUIDAR
摘要
The present invention relates to a method of treating patients with solid tumors, leukemias, and other malignancies using a combination of zosuquidar and a calicheamicin-antibody conjugate, such as Mylotarg. The invention is also directed to pharmaceutical formulations comprising zosuquidar and calicheamicin-antibody conjugates. The formulations are particularly effective in treating relapsed Acute Myelogenous Leukemia (AML) and metastatic breast cancer.
申请公布号
CA2614321(A1)
申请公布日期
2007.01.18
申请号
CA20062614321
申请日期
2006.06.30
申请人
KANISA PHARMACEUTICALS, INC.
发明人
MULTANI, PRATIK S.;WALSH, MICHAEL J.;MARCELLETTI, JOHN;GLENN, SCOTT;SOCKS, DAVID;SIKIC, BRANIMIR;HOTH, DANIEL