METHOD FOR SEQUENCING PEPTIDES AND PROTEINS USING METASTABLE-ACTIVATED DISSOCIATION MASS SPECTROMETRY

摘要

Methods for fragmentation of large molecular ions, including proteins, nucleic acids, dendromers, and nanomaterials, compatible with several mass spectrometric techiniques. The methods involve providing a gas-phase ion and allowing the gas phase ion to undergo collisions with metastable states of noble gases or nitrogen gas.