LEADER SEQUENCES FOR DIRECTING SECRETION OF POLYPEPTIDES AND METHODS FOR PRODUCTION THEREOF
摘要
The present invention provides leader sequences that are useful for the production of heterologous secretable polypeptides; heterologous secreted polypeptides; nucleic acid constructs that encode such leader sequences and heterologous secreted polynucleotides; vectors that contain such nucleic acid constructs; recombinant host cells that contain such nucleic acid constructs; vectors, polypeptides, and methods of making and using such secreted polypeptides with such heterologous leader sequences.
申请公布号
WO2006081430(A9)
申请公布日期
2006.11.30
申请号
WO2006US02951
申请日期
2006.01.27
申请人
FIVE PRIME THERAPEUTICS, INC.;HALENBECK, ROBERT, FORGAN;BOSCH, ELIZABETH;LINNEMANN, THOMAS;LEE, ERNESTINE