CRF peptide analogs that bind to CRFR2 with an affinity far greater than they bind to CRFR1. These analogs exhibit CRF antagonist activity, and they can be based upon the native structures of sauvagine, CRF, and urocortin.
申请公布号
US7141546(B1)
申请公布日期
2006.11.28
申请号
US20020210889
申请日期
2002.07.31
申请人
THE SALK INSTITUTE FOR BIOLOGICIAL STUDIES
发明人
RIVIER JEAN E. F.;VALE WYLIE W.;PERRIN MARILYN H.;GULYAS JOZSEF;KIRBY DEAN A.
