NOVEL STROMAL CELL-DERIVED FACTOR-1 POLYPEPTIDES, POLYNUCLEOTIDES, MODULATORS THEREOF, AND METHOD OF USE

摘要

Disclosed herein is a newly identified SDF-1 splice variant molecule, its polypeptide sequence, and the polynucleotides encoding the polypeptide sequence, and active fragments thereof. Also provided is a procedure for producing such polypeptides by recombinant techniques e4mploying, for example, vectors and host cells. Also disclosed are methods for utilizing such polypeptides modulators thereof for the treatment of diseases, including cancer, immune diseases, infectious diseases, and ischemic diseases.