BEAD FOR OPTICAL-ISOMER RESOLUTION AND PROCESS FOR PRODUCING THE SAME

摘要

A process for producing beads for optical-isomer resolution which have a satisfactory separation efficiency. The beads for optical-isomer resolution comprise a polysaccharide derivative, wherein the polysaccharide derivative has a structure crosslinked at the 6-position hydroxy group in constituent units of the polysaccharide with a crosslinking agent. The process for producing the beads for optical-isomer resolution comprises: a step in which an organic solvent solution of the polysaccharide derivative is added dropwise to a coagulation bath being stirred to thereby produce beads; a step in which the beads are taken out and then dried optionally after cleaning; and a step in which the beads are reacted with a crosslinking agent in an organic solvent to react at least part of the 6-position hydroxy groups in the constituent units of the polysaccharide with the crosslinking agent and thereby obtain a reaction mixture containing beads having a crosslinked structure.