| 发明名称 |
ENZIMA ESFINGOSINA QUINASA. |
| 摘要 |
The present invention relates generally to novel protein molecules and to derivatives, analogues, chemical equivalents and mimetics thereof capable of modulating cellular activity and, in particular, modulating cellular activity via the modulation of signal transduction. More particularly, the present invention relates to human sphingosine kinase and to derivatives, analogues, chemical equivalents and mimetics thereof. The present invention also contemplates genetic sequences encoding said protein molecules and derivatives, analogues, chemical equivalents and mimetics thereof. The molecules of the present invention are useful in a range of therapeutic, prophylactic and diagnostic applications.
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| 申请公布号 |
ES2261200(T3) |
申请公布日期 |
2006.11.16 |
| 申请号 |
ES20000926537T |
申请日期 |
2000.05.12 |
| 申请人 |
JOHNSON & JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT LLC |
发明人 |
PITSON, STUART, MAXWELL;WATTENBERG, BRIAN, WOLFF;XIA, PU;D'ANDREA, RICHARD, JAMES;GAMBLE, JENNIFER, RUTH;VADAS, MATHEW, ALEXANDER |
| 分类号 |
G01N33/53;A61K31/711;A61K38/00;A61K38/43;A61K38/55;A61K39/395;A61K45/00;A61K48/00;A61P9/10;A61P11/06;A61P25/00;A61P25/28;A61P29/00;A61P31/10;A61P43/00;C07K16/40;C12N5/00;C12N5/10;C12N9/12;C12N9/96;C12N15/09;C12P21/08;C12Q1/48;C12Q1/68;G01N33/577;(IPC1-7):C12N9/12;A61K38/45;C07K16/18 |
主分类号 |
G01N33/53 |
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