PYRIDONE-CARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF AND ANTI-TUMOR AGENTS CONTAINING THE PYRIDONE-CARBOXYLIC ACID DERIVATIVES

摘要

A pyridonecarboxylic acid derivative represented by general formula (a) or a salt thereof, a process for producing the compounds, and an antitumor agent containing the same as the active ingredient, wherein R1 represents hydrogen , halogen, etc.; R2 represents carboxy, etc.; R3 represents hydrogen, etc.; A represents nitrogen or CH; m represents 1 or 2; Y represents an eliminable group or a group represented by general formula (b); R4 represents hydrogen or lower alkyl; Z represents hydrogen, lower alkyl, etc.; R5 represents hydroge n, lower alkyl, etc.; n represents 0 or 1; and p represents 1, 2, 3 or 4.