| 摘要 |
<p num="1"><br/><br/><br/>Compounds of the formula: (I) or solvate thereof, wherein: R2 is an optionally <br/>substituted C5-20 aryl group; R6 and R9 are independently selected from H, R, <br/>OH, OR, SH, SR, NH2, NHR, NRR'', nitro, Me3Sn and halo; where R and R'' are <br/>independently selected from optionally substituted C1-12 alkyl, C3-20 <br/>heterocyclyl and C5-20 aryl groups; R7 is selected from H, R, OH, OR, SH, SR, <br/>NH2, NHR, NHRR'', nitro, Me3Sn and halo; R" is a C3-12 alkylene group, which <br/>chain may be interrupted by one or more heteroatoms and/or aromatic rings; X <br/>is selected from O, S, or NH; z is 2 or 3; M is a monovalent pharmaceutically <br/>acceptable cation; R2'', R6'', R7'', R9'', X'' and M'' are selected from the same <br/>groups as R2, R6, R7, R9, X and M respectively, or M and M'' may together <br/>represent a divalent pharmaceutically acceptable cation.<br/>
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