发明名称 |
PROCESS FOR PREPARING A HUMAN PAPILLOMAVIRUS VACCINE WITH DISASSEMBLED AND REASSEMBLED VIRUS-LIKE PARTICLES |
摘要 |
<p>Human Papillomavirus vaccine formulations which contain virus-like particles (VLPs) can be made more stable and have an enhanced shelf-life, by treating the VLPs to a disassembly and reassembly process. Also provided are formulation buffers to long term stable storage of VLPs.</p> |
申请公布号 |
EP1165126(B1) |
申请公布日期 |
2006.09.13 |
申请号 |
EP20000918248 |
申请日期 |
2000.03.22 |
申请人 |
MERCK & CO., INC. |
发明人 |
VOLKIN, DAVID, B.;MACH, HENRYK;SHI, LI |
分类号 |
A61K9/08;A61K39/12;A61K47/02;A61K47/14;A61K47/16;A61K47/34;A61P31/12 |
主分类号 |
A61K9/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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