| 发明名称 |
Nucleic acids encoding anti-human alphanubeta3 and alphanubeta5 antibodies |
| 摘要 |
This invention relates to novel humanized and other recombinant or engineered antibodies or monoclonal antibodies to a human alpha<SUB>v </SUB>subunit-containing heterodimeric integrin receptors and to the genes encoding same. Such antibodies are useful for the therapeutic and/or prophylactic treatment of disorders mediated by such receptors, such as cancer, in human patients.
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| 申请公布号 |
US7087405(B2) |
申请公布日期 |
2006.08.08 |
| 申请号 |
US20020141908 |
申请日期 |
2002.05.09 |
| 申请人 |
SMITHKLINE BEECHAM CORPORATION |
发明人 |
JOHANSON KYUNG O;JONAK ZDENKA LUDMILA;TAYLOR ALEXANDER;TRULLI STEPHEN H |
| 分类号 |
C12P21/06;G01N33/50;A61K39/395;A61K45/00;A61P9/10;A61P27/02;A61P29/00;A61P35/00;A61P35/04;A61P43/00;C07K14/47;C07K16/28;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12P21/08;G01N33/15;G01N33/53;G01N33/566;G01N33/577 |
主分类号 |
C12P21/06 |
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