2-(CYCLIC AMINOCARBONYL)INDOLINE DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THE SAME

摘要

A compound represented by the following formula (I), which selectively acts on a mitochondrial benzodiazepine receptor and is useful as a remedy and preventive for anxiety disorders, depression, epilepsy, demential diseases, etc.; and a pharmaceutically acceptable acid addition salt thereof. (I) [In the formula, A represents a group represented by the following formula (I-A): (I-A) (wherein X represents oxygen or sulfur; R<SUP>4</SUP> represents hydrogen, C<SUB>1-6</SUB> alkyl, etc.; and R<SUP>5</SUP> represents hydrogen, etc.), heteroaryl optionally substituted by halogeno, C<SUB>1-6</SUB> alkyl, or C<SUB>1-6</SUB> alkoxy, etc.; R<SUP>1</SUP> and R<SUP>2</SUP> are the same or different and each represents hydrogen, C<SUB>1-6</SUB> alkyl, etc.; R<SUP>3</SUP> represents hydrogen, halogeno, C<SUB>1-6</SUB> alkoxy, etc.; R<SUP>a</SUP> and R<SUP>b</SUP> are the same or different and each represents hydrogen or C<SUB>1-6</SUB> alkyl; and n is an integer of 0-5.]