| 发明名称 |
Phosphodiesterase 10 inhibitors |
| 摘要 |
The present disclosure relates generally to the field of phosphodiesterase 10 (PDE10) enzyme inhibition by cinnoline compounds of Formulas I and II: wherein R<SUP>1</SUP>-R<SUP>3 </SUP>and R<SUP>15</SUP>-R<SUP>18 </SUP>are as defined herein. The disclosure also relates to methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
|
| 申请公布号 |
US2006160814(A1) |
申请公布日期 |
2006.07.20 |
| 申请号 |
US20050217664 |
申请日期 |
2005.09.02 |
| 申请人 |
ARRINGTON MARK P;LIU RUIPING;CONTICELLO RICHARD D;GAUSS CARLA M;HOPPER ALLEN;NGUYEN TRUC M;TEHIM ASHOK |
发明人 |
ARRINGTON MARK P.;LIU RUIPING;CONTICELLO RICHARD D.;GAUSS CARLA M.;HOPPER ALLEN;NGUYEN TRUC M.;TEHIM ASHOK |
| 分类号 |
A61K31/502;C07D403/02 |
主分类号 |
A61K31/502 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
