发明名称 |
Light induced immobilisation |
摘要 |
The present invention involves a method of coupling disulfide bridge containing proteins to a carrier by inducing the formation of thiol groups on a protein with irradiation, and coupling the protein to the carrier. The formation of thiol group(s) in the protein is a consequence of the disruption of disulfide bridges following electronic excitation of aromatic amino acid residues located in close spacial proximity to the disulfide bridge. The light-induced coupling method facilitates the orientated immobilization of a protein on a carrier.
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申请公布号 |
US2006153922(A1) |
申请公布日期 |
2006.07.13 |
申请号 |
US20050542159 |
申请日期 |
2005.11.01 |
申请人 |
BIONANOPHOTONICS A/S |
发明人 |
PETERSEN STEFFEN B.;DA CRUZ AUGUSTO NEVES PETERSEN MARIA T. |
分类号 |
A61K9/14;C07K16/46;C07K17/00;C12N11/16;G01N33/68 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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