发明名称 |
RING-CLOSING METATHESIS PROCESS IN SUPERCRITICAL FLUID |
摘要 |
<p>Disclosed is a process for preparing a compound of formula I comprising cyclizing a diene compound of formula III in the presence of a ruthenium catalyst in a suitable organic solvent, wherein the process is performed in a gaseous fluid at supercritical or near-supercritial conditions. The compounds of formula I are active agents for the treatment of hepatitis C viral (HCV) infections or are intermediates useful for the preparation of anti-HCV agents.</p> |
申请公布号 |
WO2006033851(A1) |
申请公布日期 |
2006.03.30 |
申请号 |
WO2005US32100 |
申请日期 |
2005.09.09 |
申请人 |
BOEHRINGER INGELHEIM INTERNATIONAL, GMBH;GALLOU, FABRICE;YEE, NATHAN |
发明人 |
GALLOU, FABRICE;YEE, NATHAN |
分类号 |
C07K1/00;A61K38/06;A61P31/14 |
主分类号 |
C07K1/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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