发明名称 |
USING RECEPTOR AT-1 ANTAGONIST OR RECEPTOR AT-2 MODULATOR IN TREATMENT OF DISEASES ASSOCIATED WITH INCREASE CONTENT OF AT-1 OR AT-2 RECEPTORS |
摘要 |
FIELD: medicine, oncology. ^ SUBSTANCE: invention proposes using a medicine valsartan as an antagonist of AT-1 receptors and a modulator of AT-2 receptors in treatment of lung or mammary glands invasive cancer. All carcinomas comprise AT-2 receptors while in hyperplasia of normal epithelial cells AT-2 receptors are localized only. This allows carrying out both diagnosis of malignant tumor development and treatment indicated diseases with valsartan owing to modulation of AT-2 receptors, i. e. based on change of the host biological response for tumor cells. ^ EFFECT: improved and valuable medicinal properties of medicine agent. ^ 13 tbl, 12 ex |
申请公布号 |
RU2271809(C2) |
申请公布日期 |
2006.03.20 |
申请号 |
RU20010119990 |
申请日期 |
1999.12.22 |
申请人 |
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发明人 |
BALLOK DZHILLIAN ROUZMARI;DE-GASPARO MARK;GANTER ZABINA MARIJA |
分类号 |
A61K31/41;A61K9/20;A61K9/28;A61K31/00;A61K31/415;A61K31/4178;A61K31/4188;A61K31/437;A61K31/44;A61K31/4439;A61K31/455;A61K45/00;A61K47/32;A61K47/38;A61P1/18;A61P9/12;A61P11/00;A61P11/06;A61P17/02;A61P35/00 |
主分类号 |
A61K31/41 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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