发明名称 PYRROLE-2, 5-DIONE DERIVATIVES AS LIVER X RECEPTOR MODULATORS.
摘要 <p>The present invention relates to certain novel compounds of the Formula (I) to processes for preparing such compounds, to their the utility in modulation of nuclear hormone receptors Liver X Receptor (LXR) alpha (NR1H3) and/or beta (NR1H2) and in treating and/or preventing clinical conditions including cardiovascular diseases such as atherosclerosis; inflammatory diseases, Alzheimer's disease, lipid disorders (dyslipidemias) whether or not associated with insulin resistance, type 2 diabetes and other manifestations of the metabolic syndrome, to methods for their therapeutic use and to pharmaceutical compositions containing them.</p>
申请公布号 MXPA06000414(A) 申请公布日期 2006.03.17
申请号 MX2006PA00414 申请日期 2004.07.08
申请人 ASTRAZENECA AB 发明人 CHRISTER WESTERLUND
分类号 A61K31/4025;A61K31/4439;A61P3/10;A61P25/28;C07D207/416;C07D207/44;C07D207/456;C07D401/06;C07D405/06;C07D405/12;C07D405/14;C07D413/06;(IPC1-7):A61K31/402;A61K31/443 主分类号 A61K31/4025
代理机构 代理人
主权项
地址