ONCOFETAL FIBRONECTIN AS A MARKER FOR DISEASE AND OTHER CONDITIONS AND METHODS FOR DETECTION OF ONCOFETAL FIBRONECTIN

摘要

A method for classifying the level of oncofetal fibronectin in a sample comprises measuring the amount of an oncofetal fibronectin indicating molecule in a sample;
comparing the amount of oncofetal fibronectin indicating molecule in the sample to two or more threshold levels derived from the source of the oncofetal fibronectin and classifying the amount of oncofetal fibronectin indicating molecule in the sample according to the highest threshold level that is less than or equal to amount of the oncofetal fibronectin indicating molecule in the sample. The lower threshold may be 50 ng/ml and the higher threshold may be 150 ng/ml. A kit comprises a fibronectin or oncofetal fibronectin binding partner, a non-specific binder, a solid support containing a non-specific binding surface or a sample collection device; and a system for classifying the subject with respect to multiple thresholds.