发明名称 PHARMAZEUTISCHE ZUSAMMENSETZUNGEN ENTHALTEND LYSOSTAPHIN ALLEIN ODER IN KOMBINATION MIT EINEM ANTIBIOTIKUM ZUR BEHANDLUNG VON STAPHYLOKOKKENINFEKTIONEN
摘要 Lysostaphin is demonstrated to be a powerful anti-staphylococcal agent suitable for parenteral administration to mammals including humans. Low dosages, on the order of 0.5 - 45 mg/kg/day are sufficient to eradicate most staphylococcal infections. Lysostaphin is also effective against bacteria of this type which have developed resistance to conventional antibiotics such as penicillins and vancomycin. Lysostaphin analogues, such as variants and related enzymes, show similar activity.
申请公布号 AT316794(T) 申请公布日期 2006.02.15
申请号 AT19980935954T 申请日期 1998.07.21
申请人 AMBI INC. 发明人 GOLDSTEIN, BETH, P.;CLIMO, MICHAEL, W.;NOVICK, RICHARD, P.;ARCHER, GORDON, L.
分类号 A61K38/46;A61K38/48;A61K45/00;A61P31/04 主分类号 A61K38/46
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