发明名称 |
AZETIDINECARBOXAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF CB1 RECEPTOR MEDIATED DISORDERS |
摘要 |
Compounds of formula (I) and their use in therapy, particularly for the treatment of a disorder mediated by CB1 receptors such as obesity: Formuila (I) wherein: R1 and R2 are independently selected from aryl; and R3 is hydrogen or alkyl; or a pharmaceutically acceptable salt or prodrug thereof, wherein at least one of R1 and R2 has a non- hydrogen substituent in the ortho-position(s) thereof relative to the point of attachment to the [-CH-0-] group.
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申请公布号 |
KR20060010770(A) |
申请公布日期 |
2006.02.02 |
申请号 |
KR20057020649 |
申请日期 |
2005.10.31 |
申请人 |
VERNALIS RESEARCH LIMITED |
发明人 |
DAVIDSON JAMES EDWARD PAUL;DAWSON CLAIRE ELIZABETH;HARRISON KERRY;MANSELL HOWARD LANGHAM;PRATT ROBERT MARK;SOHAL SUHKJIT;RUSTON VICTORIA JANE |
分类号 |
C07D205/04;A61P3/04;A61P25/00;C07D405/12;C07D409/12 |
主分类号 |
C07D205/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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