发明名称 POLYMORPHS OF 2-(3-CYANO-4-ISOBUTYLOXYPHENYL)-4-METHYL-5-THIAZOLECARBOXYLIC ACID AND METHOD FOR THEIR PREPARATION
摘要 The invention relates to a method for selective production of polymorph of 2-(3-cyano-4-isobutyloxyphenyl)-4-methyl-5-thiazolecarboxylic acid and to a method for the preparation of its different polymorphs, including crystallization, determined from specific temperature and the composition of a mixed solvent of methanol and water, as well as to polymorphs produced by this method. The invention also relates to a method for the preparation of the other polymorphs or of amorphous compounds by drying of a specific polymorph at reduced pressure and heating, as well as to the other polymorphs or amorphous compounds produced by this method.
申请公布号 BG64734(B1) 申请公布日期 2006.01.31
申请号 BG20000104159 申请日期 2000.02.16
申请人 TEIJIN LTD. 发明人 MATSUMOTO KOICHI;WATANABE KENZO;HIRAMATSU TOSHIYUKI;KITAMURA MITSUTAKA;MAEDA SUMIHIRO
分类号 C07D277/00;C07D277/56 主分类号 C07D277/00
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