发明名称 METHOD FOR PRODUCTION OF DIAGNOSIS SERUM AGAINST L-FORM BRUCELLA
摘要 FIELD: veterinary microbiology. ^ SUBSTANCE: claimed method includes providing of stable culture from B.abortus 19 strain in L-form followed by rabbit immunization. Culture is obtained in dense broth containing additionally 10-15 % of normal hoarse serum wherein broth is singly exposed to streptomycin action in dose of 2.5-5.0 U/ml of medium. Then slurry is prepared from obtained culture, inactivated at 85-90°C for 160 min and triply intravenously administrated to rabbits in increasing doses with 72 h intervals. ^ EFFECT: method for more exact estimation of brucelliasis epizootic situation on basis of typical, dissociated and deep-altered brucella forms. ^ 6 tbl, 4 ex
申请公布号 RU2268748(C2) 申请公布日期 2006.01.27
申请号 RU20030121773 申请日期 2003.07.15
申请人 发明人 OSHCHEPKOV VLADIMIR GRIGOR'EVICH;GORDIENKO LJUBOV' NIKOLAEVNA;BRATTSEV ALEKSANDR JUR'EVICH
分类号 A61K39/40;C12N1/20;G01N33/531 主分类号 A61K39/40
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