MANUFACTURE OF ESTERS USING A MULTIPLE CATALYST APPROACH

摘要

Esters are prepared from hydroxyl-containing compounds and carboxylic acids or anhydrides or lower alkyl esters thereof using a multiple catalyst approach, wherein a first catalyst such as an organotin catalyst can be present at the beginning of the reaction and a second catalyst such as an organotitanium catalyst can be added any time after the addition of the first catalyst, or when the acid value of the reaction mixture falls below a predetermined acid value. The second catalyst can be added multiple times, and a third or additional catalysts can also be used.