Instrument and system for pharmacologic measurement and well vessel used therein

摘要

It is an object of the invention to provide an instrument for pharmacologic measurement capable of detecting a very small and short time change in electric signal caused by a pharmacologic action of a biologic specimen with quickness and a high sensitivity by steeply decreasing an external disturbance component mixed into the system while dropping/exchange of medicinal solutions is conducted in a batch mode. The pharmacologic measurement instrument 20 detects a change in electric signal caused by a pharmacologic action or electrophysiologic action of a biologic specimen, and includes: an electrically conductive box 2 having an opening section 8 at the top surface thereof; and a well vessel 19 disposed in the opening section 8 thereof, wherein the well vessel 19 includes: a base 1 having recesses 4 in which the biologic specimens 6 are put; measurement electrodes 10 formed on the bottom surfaces of the respective recesses 4; and reference electrodes 13 electrically insulated from the respective measurement electrodes 10, and the reference electrodes 13 together with the electrically conductive box 2 electrostatically shields the well vessel 19.