发明名称 |
Kappa opioid receptor ligands |
摘要 |
Kappa opioid receptor antagonists are provided that yield significant improvements in functional binding assays to kappa opioid receptors relative to nor-BNI, and the use of these antagonists in treatment of disease states that are ameliorated by binding of the kappa opioid receptor such as heroin or cocaine addictions.
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申请公布号 |
US6974824(B2) |
申请公布日期 |
2005.12.13 |
申请号 |
US20010755021 |
申请日期 |
2001.01.08 |
申请人 |
RESEARCH TRIANGLE INSTITUTE |
发明人 |
CARROLL F. IVY;THOMAS JAMES B.;MASCARELLA S. WAYNE |
分类号 |
C07D211/22;A61K31/445;A61K31/4725;A61P25/04;A61P25/36;A61P43/00;C07D401/12;(IPC1-7):A61K31/445;C07D251/00;C07D401/00;C07D217/00;C07D487/00 |
主分类号 |
C07D211/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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