METHOD FOR IDENTIFYING INHIBITORS USING A HOMOLOGY MODEL OF POLO-LIKE KINASE 1
摘要
The present invention relates to a homology model for PLK, and the use thereof in assays for the indentification of small molecule PLK modulators. The invention further relates to PLK modulators identified by said assays, and their use in the treatment of PLK-related disorders such as proliferative disorders.
申请公布号
WO2005047526(A3)
申请公布日期
2005.12.08
申请号
WO2004GB04762
申请日期
2004.11.12
申请人
CYCLACEL LIMITED;MCINNES, CAMPBELL;MCLACHLAN, JANICE;MEZNA, MOKDAD;FISCHER, PETER
发明人
MCINNES, CAMPBELL;MCLACHLAN, JANICE;MEZNA, MOKDAD;FISCHER, PETER
