发明名称 METHOD AND COMPOSITION FOR CELLULAR REPROGRAMMING
摘要 PROBLEM TO BE SOLVED: To provide methods and compositions useful in treating certain diseases herein termed "Aberrant Programming Diseases", including cancer and AIDS. SOLUTION: The method for treating an individual having an Aberrant Programming Disease comprises administering to the individual an effective amount of a composition selected from the group consisting of an expression vector, a double stranded oligodeoxynucleotide, and an antisense oligodeoxynucleotide, wherein the composition is capable of regulating expression of a transcriptional regulator, the transcriptional regulator being expressed by the Aberrant Programming cells, and further characterised by exhibiting a therapeutically useful change in the cell behaviour in a Programming Test. In a separate embodiment, new antisense oligodeoxynucleotides are provided. COPYRIGHT: (C)2006,JPO&NCIPI
申请公布号 JP2005320337(A) 申请公布日期 2005.11.17
申请号 JP20050147562 申请日期 2005.05.20
申请人 BOARD OF REGENTS OF THE UNIV OF NEBRASKA 发明人 SMITH LARRY J
分类号 C12N15/09;A61K31/70;A61K31/7088;A61K31/7125;A61K38/00;A61K48/00;A61P31/18;A61P35/00;C07H21/04;C12N15/113;C12Q1/68;(IPC1-7):A61K48/00;A61K31/708;A61K31/712 主分类号 C12N15/09
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