发明名称 |
Quantitative multiplex amplification on a genomic scale, and applications for detecting genomic rearrangements |
摘要 |
The present application relates to novel composite primers which make it possible to amplify in multiplex at a quantitative level of precision, and to the application of these composite primers for detecting gnomic rearrangements in general and cryptic chromosomal rearrangements in particular. These composite primers contain a tag the sequence of which is absent from or poorly represented in the genome analyzed, and which exhibits a very low propensity to form stable pairings. The composite primers, which contain them, make it possible to carry out multiplex amplifications with quantitative precision on the scale of a genome such as the human genome.
|
申请公布号 |
US2005244830(A1) |
申请公布日期 |
2005.11.03 |
申请号 |
US20050521721 |
申请日期 |
2005.04.18 |
申请人 |
FREBOURG THIERY;TOSI MARIO;RAUX GREGORY |
发明人 |
FREBOURG THIERY;TOSI MARIO;RAUX GREGORY |
分类号 |
C12Q1/68;(IPC1-7):C12Q1/68;C07H21/04 |
主分类号 |
C12Q1/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|