PSEUDO-THERMOSETTING NEUTRALIZED CHITOSAN COMPOSITION FORMING A HYDROGEL AND A PROCESS FOR PRODUCING THE SAME

摘要

The composition disclosed is a pseudo-thermosetting neutralized chitosan composition, neutralized with an hydroxylated base, forming a phosphate-free transparent hydrogel at a temperature higher than 5°C. Said composition contains a homogeneously reacetylated chitosan derived from a chitosan having a deacetylation degree of 80 - 90 %, having a molecular weight of not smaller than 200 kDa and a deacetylation degree of 30 - 60 %, and may further contain a diol. Said composition may be used as a drug delivery system.